Publications

Comparative structural analysis provides new insights into the function of R2‐like ligand‐binding oxidase

Diamanti, Riccardo; Srinivas, Vivek; Johansson, Annika I.; Nordström, Anders et al.

Part of FEBS Letters, p. 1600-1610, 2022.

DOI for Comparative structural analysis provides new insights into the function of R2‐like ligand‐binding oxidase Download full text (pdf) of Comparative structural analysis provides new insights into the function of R2‐like ligand‐binding oxidase

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The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout

Marcos-Torres, Francisco Javier; Maurer, Dirk; Juniar, Linda; Griese, Julia J.

Part of Nucleic Acids Research, 2021.

DOI for The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout Download full text 1 (pdf) of The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout Download full text 2 (pdf) of The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout

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The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron

Grāve, Kristīne; Griese, Julia J.; Berggren, Gustav; Bennett, Matthew D. et al.

Part of Journal of Biological Inorganic Chemistry, p. 571-582, 2020.

DOI for The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron Download full text (pdf) of The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron

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Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein

Kisgeropoulos, Effie C.; Griese, Julia J.; Smith, Zachary R.; Branca, Rui M. M. et al.

Part of Journal of the American Chemical Society, p. 5338-5354, 2020.

DOI for Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein Download full text (pdf) of Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein

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Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase

Griese, Julia J.; Kositzki, Ramona; Haumann, Michael; Hogbom, Martin

Part of Journal of Biological Inorganic Chemistry, p. 211-221, 2019.

DOI for Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase Download full text (pdf) of Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase

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Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access

Grāve, Kristīne; Lambert, Wietske; Berggren, Gustav; Griese, Julia J. et al.

Part of Journal of Biological Inorganic Chemistry, p. 849-861, 2019.

DOI for Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access Download full text (pdf) of Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access

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Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins

Kutin, Yury; Kositzki, Ramona; Branca, Rui M.M.; Srinivas, Vivek et al.

Part of Journal of Biological Chemistry, p. 18372-18386, 2019.

DOI for Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins Download full text (pdf) of Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins

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Solving a new R2lox protein structure by microcrystal electron diffraction

Xu, Hongyi; Lebrette, Hugo; Clabbers, Max T. B.; Zhao, Jingjing et al.

Part of Science Advances, 2019.

DOI for Solving a new R2lox protein structure by microcrystal electron diffraction Download full text (pdf) of Solving a new R2lox protein structure by microcrystal electron diffraction

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Location-specific quantification of protein-bound metal ions by X-ray anomalous dispersion: Q-XAD

Griese, Julia J.; Högbom, Martin

Part of Acta Crystallographica Section D, p. 764-771, 2019.

DOI for Location-specific quantification of protein-bound metal ions by X-ray anomalous dispersion: Q-XAD Download full text (pdf) of Location-specific quantification of protein-bound metal ions by X-ray anomalous dispersion: Q-XAD

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Fate of oxygen species from O₂ activation at dimetal cofactors in an oxidase enzyme revealed by ⁵⁷Fe nuclear resonance X-ray scattering and quantum chemistry

Mebs, Stefan; Srinivas, Vivek; Kositzki, Ramona; Griese, Julia J. et al.

Part of Biochimica et Biophysica Acta - Bioenergetics, 2019.

DOI for Fate of oxygen species from O₂ activation at dimetal cofactors in an oxidase enzyme revealed by ⁵⁷Fe nuclear resonance X-ray scattering and quantum chemistry
DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

Sustmann, Claudio; Dickopf, Steffen; Regula, Jörg T.; Kettenberger, Hubert et al.

Part of mAbs, p. 1402-1414, 2019.

DOI for DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity Download full text (pdf) of DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

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Ether cross-link formation in the R2-like ligand-binding oxidase

Griese, Julia J.; Branca, Rui M. M.; Srinivas, Vivek; Hogbom, Martin

Part of Journal of Biological Inorganic Chemistry, p. 879-886, 2018.

DOI for Ether cross-link formation in the R2-like ligand-binding oxidase Download full text (pdf) of Ether cross-link formation in the R2-like ligand-binding oxidase

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Driving Protein Conformational Changes with Light: Photoinduced Structural Rearrangement in a Heterobimetallic Oxidase

Maugeri, Pearson T.; Griese, Julia J.; Branca, Rui M.; Miller, Effie K. et al.

Part of Journal of the American Chemical Society, p. 1471-1480, 2018.

DOI for Driving Protein Conformational Changes with Light: Photoinduced Structural Rearrangement in a Heterobimetallic Oxidase Download full text (pdf) of Driving Protein Conformational Changes with Light: Photoinduced Structural Rearrangement in a Heterobimetallic Oxidase

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Protonation State of MnFe and FeFe Cofactors in a Ligand-Binding Oxidase Revealed by X-ray Absorption, Emission, and Vibrational Spectroscopy and QM/MM Calculations

Kositzki, Ramona; Mebs, Stefan; Marx, Jennifer; Griese, Julia J. et al.

Part of Inorganic Chemistry, p. 9869-9885, 2016.

DOI for Protonation State of MnFe and FeFe Cofactors in a Ligand-Binding Oxidase Revealed by X-ray Absorption, Emission, and Vibrational Spectroscopy and QM/MM Calculations
Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins

Kutin, Yuri; Srinivas, Vivek; Fritz, Matthieu; Kositzki, Ramona et al.

Part of Journal of Inorganic Biochemistry, p. 164-177, 2016.

DOI for Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins Download full text (pdf) of Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins

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Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor

Griese, Julia J.; Kositzki, Ramona; Schrapers, Peer; Branca, Rui M. M. et al.

Part of Journal of Biological Chemistry, p. 25254-25272, 2015.

DOI for Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor Download full text (pdf) of Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor

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Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2

Carter, Megan; Jemth, Ann-Sofie; Hagenkort, Anna; Page, Brent D. G. et al.

Part of Nature Communications, 2015.

DOI for Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2 Download full text (pdf) of Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2

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Characterization of Oxygen Bridged Manganese Model Complexes Using Multifrequency ¹⁷O-Hyperfine EPR Spectroscopies and Density Functional Theory

Rapatskiy, Leonid; Ames, William M.; Pérez-Navarro, Montserrat; Savitsky, Anton et al.

Part of Journal of Physical Chemistry B, p. 13904-13921, 2015.

DOI for Characterization of Oxygen Bridged Manganese Model Complexes Using Multifrequency ¹⁷O-Hyperfine EPR Spectroscopies and Density Functional Theory Download full text (pdf) of Characterization of Oxygen Bridged Manganese Model Complexes Using Multifrequency ¹⁷O-Hyperfine EPR Spectroscopies and Density Functional Theory

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Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins

Griese, Julia J.; Srinivas, Vivek; Högbom, Martin

Part of Journal of Biological Inorganic Chemistry, p. 759-774, 2014.

DOI for Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins Download full text (pdf) of Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins

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Electronic Structural Flexibility of Heterobimetallic Mn/Fe Cofactors: R2lox and R2c Proteins

Shafaat, Hannah S.; Griese, Julia J.; Pantazis, Dimitrios A.; Roos, Katarina et al.

Part of Journal of the American Chemical Society, p. 13399-13409, 2014.

DOI for Electronic Structural Flexibility of Heterobimetallic Mn/Fe Cofactors: R2lox and R2c Proteins Download full text (pdf) of Electronic Structural Flexibility of Heterobimetallic Mn/Fe Cofactors: R2lox and R2c Proteins

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Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein

Griese, Julia J.; Roos, Katarina; Cox, Nicholas; Shafaat, Hannah S. et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 17189-17194, 2013.

DOI for Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein Download full text (pdf) of Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein

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Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain

Fenn, Sebastian; Schiller, Christian B.; Griese, Julia J.; Duerr, Harald et al.

Part of PLOS ONE, 2013.

DOI for Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain Download full text (pdf) of Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain

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X-ray reduction correlates with soaking accessibility as judged from four non crystallographically related diiron sites

Griese, Julia J.; Högbom, Martin

Part of Metallomics, p. 894-898, 2012.

DOI for X-ray reduction correlates with soaking accessibility as judged from four non crystallographically related diiron sites Download full text (pdf) of X-ray reduction correlates with soaking accessibility as judged from four non crystallographically related diiron sites

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Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain

Griese, Julia J.; Hopfner, Karl Peter

Part of Proteins, p. 558-568, 2011.

DOI for Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain Download full text (pdf) of Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain

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Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins

Griese, Julia J.; Witte, Gregor; Hopfner, Karl Peter

Part of Nucleic Acids Research, p. 3454-3465, 2010.

DOI for Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins Download full text (pdf) of Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins

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Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase

Barends, Thomas R. M.; Hartmann, Elisabeth; Griese, Julia J.; Beitlich, Thorsten et al.

Part of Nature, p. 1015-1018, 2009.

DOI for Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase
Photodynamics of blue-light-regulated phosphodiesterase BlrP1 protein from Klebsiella pneumoniae and its photoreceptor BLUF domain

Tyagi, Amit; Penzkofer, Alfons; Griese, Julia J.; Schlichting, Ilme et al.

Part of Chemical Physics, p. 130-141, 2008.

DOI for Photodynamics of blue-light-regulated phosphodiesterase BlrP1 protein from Klebsiella pneumoniae and its photoreceptor BLUF domain
Xenobiotic Reductase A in the Degradation of Quinoline by Pseudomonas putida 86: Physiological Function, Structure and Mechanism of 8-Hydroxycoumarin Reduction

Griese, Julia J.; P. Jakob, Roman; Schwarzinger, Stephan; Dobbek, Holger

Part of Journal of Molecular Biology, p. 140-152, 2006.

DOI for Xenobiotic Reductase A in the Degradation of Quinoline by Pseudomonas putida 86: Physiological Function, Structure and Mechanism of 8-Hydroxycoumarin Reduction

Publications

Comparative structural analysis provides new insights into the function of R2‐like ligand‐binding oxidase

The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout

The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron

Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein

Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase

Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access

Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins

Solving a new R2lox protein structure by microcrystal electron diffraction

Location-specific quantification of protein-bound metal ions by X-ray anomalous dispersion: Q-XAD

Fate of oxygen species from O₂ activation at dimetal cofactors in an oxidase enzyme revealed by ⁵⁷Fe nuclear resonance X-ray scattering and quantum chemistry

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

Ether cross-link formation in the R2-like ligand-binding oxidase

Driving Protein Conformational Changes with Light: Photoinduced Structural Rearrangement in a Heterobimetallic Oxidase

Protonation State of MnFe and FeFe Cofactors in a Ligand-Binding Oxidase Revealed by X-ray Absorption, Emission, and Vibrational Spectroscopy and QM/MM Calculations

Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins

Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor

Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2

Characterization of Oxygen Bridged Manganese Model Complexes Using Multifrequency ¹⁷O-Hyperfine EPR Spectroscopies and Density Functional Theory

Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins

Electronic Structural Flexibility of Heterobimetallic Mn/Fe Cofactors: R2lox and R2c Proteins

Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein

Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain

X-ray reduction correlates with soaking accessibility as judged from four non crystallographically related diiron sites

Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain

Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins

Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase

Photodynamics of blue-light-regulated phosphodiesterase BlrP1 protein from Klebsiella pneumoniae and its photoreceptor BLUF domain

Xenobiotic Reductase A in the Degradation of Quinoline by Pseudomonas putida 86: Physiological Function, Structure and Mechanism of 8-Hydroxycoumarin Reduction