A world-class research department
Research interests, ranging all the way from cell biology down to biophysics of single molecules, are divided into seven specialty programs.
Our research
Research at the Department of Cell and Molecular Biology is focused on understanding how living organisms function at the cellular level. This is done at many different levels with different methodologies. We are divided into seven research programs which all focus on different areas of cell and molecular biology: Computational biology and Bioinformatics, Microbiology, Molecular Biology, Molecular Biophysics, Molecular Evolution, Molecular Systems Biology and Structural Biology. The scientific basis of what we do lies in biology, but our research overlaps with other areas such as medicine, computer science, mathematics, chemistry, engineering sciences and physics.
Highlighting our research
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Professor Stefan Knight -
Lisa Klasson -
Bengt Persson -
Jens Carlsson -
Peter Kasson -
Professor Suparna Sanyal -
Professor Leif Kirsebom -
Johan Elf
Publications
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A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
2019
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A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis
2019
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A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
2019
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A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
2019
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A versatile liquid-jet setup for the European XFEL
2019
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Ab initio phasing of the diffraction of crystals with translational disorder
2019
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Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580
2019
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Allele specific chromatin signals, 3D interactions, and motif predictions for immune and B cell related diseases
2019
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An archaeal symbiont-host association from the deep terrestrial subsurface
2019
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Analyzing DNA methylation patterns in subjects diagnosed with schizophrenia using machine learning methods
2019
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Asgard archaea capable of anaerobic hydrocarbon cycling
2019
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Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase
2019
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ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes
2019
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Chromosomal genome assembly of the ethanol production strain CBS 11270 indicates a highly dynamic genome structure in the yeast species Brettanomyces bruxellensis
2019
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Class II contact‐dependent growth inhibition (CDI) systems allow for broad‐range cross‐species toxin delivery within the Enterobacteriaceae family
2019
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Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins
2019
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Comparative genomics of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members emphasizing tRNA and non-coding RNA
2019
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Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing
2019
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Confident phylogenetic identification of uncultured prokaryotes through long read amplicon sequencing of the 16S-ITS-23S rRNA operon
2019
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Copy number determination of the gene for the human pancreatic polypeptide receptor NPY4R using read depth analysis and droplet digital PCR.
2019
Dissertations
Public defences and licentiate seminars
Revolutionary discovery
PhD courses for 2019
- This Academic Teacher Training Course is offered to international teachers and researchers as well as doctoral students who will be spending extensive periods of time at Uppsala University and taking part in teaching. Organizer: Division for Quality Enhancement, Academic Teaching and Learning. During the Autumn 2018 and the Spring 2019 there will be three opportunities to do the course in English. For more information please see calendar.
Working with infectious substances
- For those who don’t have the experience or are not familiar with the Swedish laws and regulations governing work with infectious substances or GMM, there is a one day course held several times each semester. During this course we will discuss the organization of Uppsala University, Swedish laws and ordinances, work with infectious substances, incidents and accidents, practical risk assessments, and there is an exercise with containment and clean-up of a simulated biological spill. For Ph.D students the course is worth 1 hp. Course dates 2019.
Research Ethics for Science and Technology
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This course aims at improving your capacity to reflect on your preconceptions and values with regard to problems of research ethics. All the fundamentals of research integrity and responsible conduct of research are covered by a teaching staff of experienced national experts.This 2 credit course consists of lectures, seminars, and group work. You’ll get to discuss research ethics with PhD students from the faculties of technology and natural sciences and learn from others’ experiences
Contact person: Stefan Eriksson, Senior Lecturer & Associate Professor of Research Ethics
- The Spring course will run 22 to 26 April 2019. This course is common for all new PhD students in biology. For more information: http://www.biologi.uu.se/digitalAssets/567/c_567927-l_3-k_presentation_web_introduction-to-postgraduate-studies2.pdf
Writing Scientific English for ESL (English second-language)
- The course is open to PhD students from any department in the TekNat faculty. For more information please contact Terese Bergfors. Syllabus and schedule
Advance Scientific Programming with Python
- Advanced Scientific Programming with Python is targeted towards PhD students from all disciplines who regularly use programming in their research. Our plan is to introduce our students to commonly used software development tools and help them become better programmers.
- All postgraduate students in biology are expected to take the course during their first year.
Course content:
Organisation, study plans, staff and functions in biological departments, safety and security, administrative routines, etc.
An overview of the research and research facilities at EBC and BMC, including the Botanical Garden, the Museum of Evolution, Scilifelab and the field stations
Library service and literature search
Working as a teching assistant
Popular science opportunities
To write an application
Good scientific practice
Philosophy of science
Info: Anssi Laurila, 471 6493
Research Introduction for New PhD students, 3 hp
- The course will give new PhD students an introduction to PhD studies, our local research environment and information about administrative support, bureaucratic requirements, etc.
Contact person: Mattias Klintenberg, mattias@physics.uu.se
More information: Research Introduction for New PhD students
Centers and Networks
Reserachers at ICM are involved in several national and international networks, see the respective group pages. Two networks are based at ICM: