A world-class research department
Research interests, ranging all the way from cell biology down to biophysics of single molecules, are divided into seven specialty programs.
Our research
Research at the Department of Cell and Molecular Biology is focused on understanding how living organisms function at the cellular level. This is done at many different levels with different methodologies. We are divided into seven research programs which all focus on different areas of cell and molecular biology: Computational biology and Bioinformatics, Microbiology, Molecular Biology, Molecular Biophysics, Molecular Evolution, Molecular Systems Biology and Structural Biology. The scientific basis of what we do lies in biology, but our research overlaps with other areas such as medicine, computer science, mathematics, chemistry, engineering sciences and physics.
Highlighting our research
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Professor Stefan Knight -
Lisa Klasson -
Bengt Persson -
Jens Carlsson -
Peter Kasson -
Professor Suparna Sanyal -
Professor Leif Kirsebom -
Johan Elf
Publications
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A chromosome-scale reference genome for Giardia intestinalis WB
2020
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Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
2020
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Development of a gp60-subtyping method for Cryptosporidium felis
2020
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Docking Finds GPCR Ligands in Dark Chemical Matter
2020
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Making Soup: Preparing and Validating Models of the Bacterial Cytoplasm for Molecular Simulation
2020
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Phosphoenolpyruvate carboxylase in Synechococcus PCC 7002: Oligomerization, structure, and characteristics
2020
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Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3
2020
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Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity
2020
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Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors
2020
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The role of transient resonances for ultra-fast imaging of single sucrose nanoclusters
2020
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Time-resolved imaging-based CRISPRi screening
2020
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A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
2019
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A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis
2019
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A natural toroidal microswimmer with a rotary eukaryotic flagellum
2019
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A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode
2019
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A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart
2019
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A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
2019
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A versatile liquid-jet setup for the European XFEL
2019
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A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration
2019
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Ab initio phasing of the diffraction of crystals with translational disorder
2019
Dissertations
Public defences and licentiate seminars
Revolutionary discovery
PhD courses
- This Academic Teacher Training Course is offered to international teachers and researchers as well as doctoral students who will be spending extensive periods of time at Uppsala University and taking part in teaching.
Organizer: Division for Quality Enhancement, Academic Teaching and Learning.
Working with infectious substances
- For those who don’t have the experience or are not familiar with the Swedish laws and regulations governing work with infectious substances or GMM, there is a one day course held several times each semester. During this course we will discuss the organization of Uppsala University, Swedish laws and ordinances, work with infectious substances, incidents and accidents, practical risk assessments, and there is an exercise with containment and clean-up of a simulated biological spill. For Ph.D students the course is worth 1 hp.
Research Ethics for Science and Technology
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This course aims at improving your capacity to reflect on your preconceptions and values with regard to problems of research ethics. All the fundamentals of research integrity and responsible conduct of research are covered by a teaching staff of experienced national experts.This 2 credit course consists of lectures, seminars, and group work. You’ll get to discuss research ethics with PhD students from the faculties of technology and natural sciences and learn from others’ experiences
Contact person: Stefan Eriksson, Senior Lecturer & Associate Professor of Research Ethics
Writing Scientific English for ESL (English second-language)
Advance Scientific Programming with Python
- Advanced Scientific Programming with Python is targeted towards PhD students from all disciplines who regularly use programming in their research. Our plan is to introduce our students to commonly used software development tools and help them become better programmers.
- All postgraduate students in biology are expected to take the course during their first year.
Course content:
Organisation, study plans, staff and functions in biological departments, safety and security, administrative routines, etc.
An overview of the research and research facilities at EBC and BMC, including the Botanical Garden, the Museum of Evolution, Scilifelab and the field stations
Library service and literature search
Working as a teching assistant
Popular science opportunities
To write an application
Good scientific practice
Philosophy of science
Info: Anssi Laurila, 471 6493
Research Introduction for New PhD students, 3 hp
- The course will give new PhD students an introduction to PhD studies, our local research environment and information about administrative support, bureaucratic requirements, etc.
Contact person: Mattias Klintenberg, mattias@physics.uu.se
More information: Research Introduction for New PhD students
Centers and Networks
Reserachers at ICM are involved in several national and international networks, see the respective group pages. Two networks are based at ICM: