Sanyal group reveals the mechanism of fidelity in translation by studying the mode of error induction by the anti-TB antibiotic viomycin
2019-06-07
A new study from Sanyal lab reveals how the anti-tuberculosis antibiotic viomycin induces error in translation during decoding of the genetic code on mRNA. Applying pre steady state kinetics to a fully reconstituted bacterial translation system this study delineates the actual mechanism of accurate decoding on the ribosome and puts it into the structural context, which is the added significance.
The full story can be read in eLife 2019 Jun 7;8. pii: e46124. doi: 10.7554/eLife.46124. https://elifesciences.org/articles/46124
En ny studie från Sanyal Lab avslöjar hur anti-tuberkulos-antibiotikum viomycin inducerar fel i translation under avkodning av den genetiska koden på mRNA. Genom att tillämpa pre steady state kinetik på ett fullständigt rekonstituerat bakteriellt translationssystem avgränsar de den verkliga mekanismen för korrekt avkodning på ribosomen och lägger den in i det strukturella sammanhanget, vilket är den extra betydelsen.
Den fullständiga historien kan läsas i eLife 2019 7 juni; 8. pii: e46124. doi: 10.7554 / eLife.46124. https://elifesciences.org/articles/46124
News of the department of cell and molecular biology
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Sanyal group reveals the mechanism of fidelity in translation by studying the mode of error induction by the anti-TB antibiotic viomycin
2019-06-07
A new study from Sanyal lab reveals how the anti-tuberculosis antibiotic viomycin induces error in translation during decoding of the genetic code on ... -
A new study by the Deindl group sheds light on DNA movements during nucleosome remodelling
2019-04-12
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Sanna Koskiniemi wins ERC Starting Grant
2018-07-27
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Ettema's group clarifies mitochondrial origin in Nature paper
2018-05-25
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Johansson’s and Elf’s groups report on new method for tracking tRNA kinetics in live cells
2018-05-18
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Lynn Kamerlin receives the 2018 The Svedberg Prize
2018-02-20
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Deindl group reports in Molecular Cell how a human oncogene and chromatin remodeling enzyme is switched on and off.
2017-12-07
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Elf's group measures search time for target DNA by CRISPR/Cas9 in Science paper
2017-09-28
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Selmer group explains how an enzyme evolved bifunctionality; atomic level multitasking
2017-05-24
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Erik Holmqvist and Mikael Sellin receive Ingvar Carlsson Award
2017-04-18
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Lynn Kamerlin wins Human Frontier Science programme award
2017-03-23
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Groups led by Suparna Sanyal and Johan Elf secured two research-environment grants to ICM
2017-03-01
Link to the homepage of Vetenskapsrådet (in swedish) ... -
Forster group chemistry reveals unexpected speed barrier in protein synthesis
2016-12-13
Link to the current article in the Journal of the American Chemical Society entitled "Ribosomal Peptide Syntheses from Activated Substrates Reveal ... -
The microbe that helped make us published in Nature
2016-12-06
A microbe no one has even seen could explain our origins. Link to the article at BBC.com Link to Nature - Complex archaea that bridge the ga... -
ERC Starting Grant for Sebastian Deindl
2016-09-16
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The E.coli cell cycle explained
2016-07-28
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Your self-made vaccine
2016-05-18
Link to the video clip in swedish:: http://urskola.se/Produkter/195536-Scientists-for-the-future-Your-self-made-vaccine ... -
Demystified entropy can explain enzyme catalysis
2016-02-01
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3D Mimivirus Reconstruction is Highlight of the Year in APS
2015-12-18
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Gerhart Wagner har tilldelats Rudbeckmedaljen
2015-11-30
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