Publikationer
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Antibiotic perseverance increases the risk of resistance development
Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2023.
DOI för Antibiotic perseverance increases the risk of resistance development Ladda ner fulltext (pdf) av Antibiotic perseverance increases the risk of resistance development
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Dynamics of release factor recycling during translation termination in bacteria
Ingår i Nucleic Acids Research, s. 5774-5790, 2023.
DOI för Dynamics of release factor recycling during translation termination in bacteria Ladda ner fulltext (pdf) av Dynamics of release factor recycling during translation termination in bacteria
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Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
Ingår i Nucleic Acids Research, s. 3436-3451, 2023.
DOI för Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis Ladda ner fulltext (pdf) av Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
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Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli
Ingår i RNA Biology, s. 681-692, 2023.
DOI för Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli Ladda ner fulltext (pdf) av Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli
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Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome
Ingår i Nature Communications, 2023.
DOI för Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome Ladda ner fulltext (pdf) av Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome
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Comparative genome analysis of Mycobacteria focusing on tRNA and non-coding RNA
Ingår i BMC Genomics, 2022.
DOI för Comparative genome analysis of Mycobacteria focusing on tRNA and non-coding RNA Ladda ner fulltext (pdf) av Comparative genome analysis of Mycobacteria focusing on tRNA and non-coding RNA
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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
Ingår i Nature Genetics, s. 1332-1344, 2022.
DOI för Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention Ladda ner fulltext (pdf) av Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
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Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
Ingår i Journal of Biological Chemistry, 2022.
DOI för Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation Ladda ner fulltext (pdf) av Rate-limiting hydrolysis in ribosomal release reactions revealed by ester activation
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Revisiting the Extinction of the RNA World
Ingår i Biochemistry, s. 749-751, 2022.
DOI för Revisiting the Extinction of the RNA World Ladda ner fulltext (pdf) av Revisiting the Extinction of the RNA World
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Uncovering translation roadblocks during the development of a synthetic tRNA
Ingår i Nucleic Acids Research, s. 10201-10211, 2022.
DOI för Uncovering translation roadblocks during the development of a synthetic tRNA Ladda ner fulltext (pdf) av Uncovering translation roadblocks during the development of a synthetic tRNA
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GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors
Ingår i Journal of Biological Chemistry, 2021.
DOI för GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors Ladda ner fulltext (pdf) av GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors
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In vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity
Ingår i Scientific Reports, 2021.
DOI för In vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity Ladda ner fulltext (pdf) av In vitro synthesis of 32 translation-factor proteins from a single template reveals impaired ribosomal processivity
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Kinetic Analysis Su :rests Evolution of Ribosome Snecificity in Modern Elongation Factor-Tus from "Generalist" Ancestors
Ingår i Molecular biology and evolution, s. 3436-3444, 2021.
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Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin
Ingår i Nucleic Acids Research, s. 6880-6892, 2021.
DOI för Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin
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N-6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors
Ingår i Nucleic Acids Research, s. 2684-2699, 2021.
DOI för N-6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors Ladda ner fulltext (pdf) av N-6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors
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Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation
Ingår i RNA Biology, s. 2363-2375, 2021.
DOI för Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation Ladda ner fulltext (pdf) av Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation
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Real-time measurements of aminoglycoside effects on protein synthesis in live cells
Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2021.
DOI för Real-time measurements of aminoglycoside effects on protein synthesis in live cells Ladda ner fulltext (pdf) av Real-time measurements of aminoglycoside effects on protein synthesis in live cells
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Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence
Ingår i Molecular biology and evolution, s. 2918-2930, 2020.
DOI för Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence Ladda ner fulltext (pdf) av Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence
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Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation
Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15609-15619, 2020.
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Overcoming chromoprotein limitations by engineering a red fluorescent protein
Ingår i Analytical Biochemistry, 2020.
DOI för Overcoming chromoprotein limitations by engineering a red fluorescent protein Ladda ner fulltext (pdf) av Overcoming chromoprotein limitations by engineering a red fluorescent protein
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Rationally designed Spot 42 RNAs with an inhibition/toxicity profile advantageous for engineering E. coli
Ingår i ENGINEERING REPORTS, 2020.
DOI för Rationally designed Spot 42 RNAs with an inhibition/toxicity profile advantageous for engineering E. coli Ladda ner fulltext (pdf) av Rationally designed Spot 42 RNAs with an inhibition/toxicity profile advantageous for engineering E. coli
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Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s
Ingår i International Journal of Molecular Sciences, 2020.
DOI för Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s Ladda ner fulltext (pdf) av Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s
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Screening cells for crystals: a synergistic approach
Ingår i Journal of applied crystallography, s. 1414-1415, 2020.
DOI för Screening cells for crystals: a synergistic approach Ladda ner fulltext (pdf) av Screening cells for crystals: a synergistic approach
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Selective translation by alternative bacterial ribosomes
Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 19487-19496, 2020.
DOI för Selective translation by alternative bacterial ribosomes Ladda ner fulltext (pdf) av Selective translation by alternative bacterial ribosomes
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Comparative genomics of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members emphasizing tRNA and non-coding RNA
Ingår i BMC Evolutionary Biology, 2019.
DOI för Comparative genomics of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members emphasizing tRNA and non-coding RNA Ladda ner fulltext (pdf) av Comparative genomics of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members emphasizing tRNA and non-coding RNA
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CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation
Ingår i BMC Endocrine Disorders, 2019.
DOI för CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation Ladda ner fulltext (pdf) av CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation
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Extended insight into the Mycobacterium chelonae-abscessus complex through whole genome sequencing of Mycobacterium salmoniphilum outbreak and Mycobacterium salmoniphilum-like strains
Ingår i Scientific Reports, 2019.
DOI för Extended insight into the Mycobacterium chelonae-abscessus complex through whole genome sequencing of Mycobacterium salmoniphilum outbreak and Mycobacterium salmoniphilum-like strains Ladda ner fulltext (pdf) av Extended insight into the Mycobacterium chelonae-abscessus complex through whole genome sequencing of Mycobacterium salmoniphilum outbreak and Mycobacterium salmoniphilum-like strains
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Gene miaA for post-transcriptional modification of tRNAXXA is important for morphological and metabolic differentiation in Streptomyces
Ingår i Molecular Microbiology, s. 249-265, 2019.
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Inhibition of translation termination by small molecules targeting ribosomal release factors
Ingår i Scientific Reports, 2019.
DOI för Inhibition of translation termination by small molecules targeting ribosomal release factors Ladda ner fulltext (pdf) av Inhibition of translation termination by small molecules targeting ribosomal release factors
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Insight into the biology of Mycobacterium mucogenicum and Mycobacterium neoaurum Glade members
Ingår i Scientific Reports, 2019.
DOI för Insight into the biology of Mycobacterium mucogenicum and Mycobacterium neoaurum Glade members Ladda ner fulltext (pdf) av Insight into the biology of Mycobacterium mucogenicum and Mycobacterium neoaurum Glade members
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Kinetics of D-amino acid incorporation in translation
Ingår i ACS Chemical Biology, s. 204-213, 2019.
DOI för Kinetics of D-amino acid incorporation in translation
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Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor
Ingår i mBio, 2019.
DOI för Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor Ladda ner fulltext (pdf) av Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor
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RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction
Ingår i Scientific Reports, 2019.
DOI för RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction Ladda ner fulltext (pdf) av RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction
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The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation
Ingår i eLIFE, 2019.
DOI för The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation Ladda ner fulltext (pdf) av The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation
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The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy
Ingår i Nature Communications, 2019.
DOI för The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy Ladda ner fulltext (pdf) av The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy
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Transcriptomics of cardiac biopsies reveals differences in patients with or without diagnostic parameters for heart failure with preserved ejection fraction
Ingår i Scientific Reports, 2019.
DOI för Transcriptomics of cardiac biopsies reveals differences in patients with or without diagnostic parameters for heart failure with preserved ejection fraction Ladda ner fulltext (pdf) av Transcriptomics of cardiac biopsies reveals differences in patients with or without diagnostic parameters for heart failure with preserved ejection fraction
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2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation
Ingår i Nature Structural & Molecular Biology, s. 208-216, 2018.
DOI för 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation
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Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ ions
Ingår i Nucleic Acids Research, s. 1362-1374, 2018.
DOI för Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ ions Ladda ner fulltext (pdf) av Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ ions
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C2 '-F Stereoconfiguration As a Puckering Switch for Base Stacking at the Dinucleotide Level
Ingår i Journal of Organic Chemistry, s. 2473-2478, 2018.
DOI för C2 '-F Stereoconfiguration As a Puckering Switch for Base Stacking at the Dinucleotide Level
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Catalytic O- to N-Alkyl Migratory Rearrangement: Transition Metal-Free Direct and Tandem Routes to N-Alkylated Pyridones and Benzothiazolones
Ingår i Advanced Synthesis and Catalysis, s. 3930-3939, 2018.
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Cholesterol enhances influenza binding avidity by controlling nanoscale receptor clustering
Ingår i Chemical Science, s. 2340-2347, 2018.
DOI för Cholesterol enhances influenza binding avidity by controlling nanoscale receptor clustering Ladda ner fulltext (pdf) av Cholesterol enhances influenza binding avidity by controlling nanoscale receptor clustering
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Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association
Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 4649-4654, 2018.
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Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain
Ingår i PLOS ONE, 2018.
DOI för Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain Ladda ner fulltext (pdf) av Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain
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Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)
Ingår i Nucleic Acids Research, s. 5861-5874, 2018.
DOI för Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A) Ladda ner fulltext (pdf) av Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)
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Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology
Ingår i Journal of Biological Engineering, 2018.
DOI för Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology Ladda ner fulltext (pdf) av Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology
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Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing
Ingår i Scientific Reports, 2018.
DOI för Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing Ladda ner fulltext (pdf) av Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing
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How 2 '-O-Methylation in mRNA Disrupts tRNA Decoding during Translation Elongation
Ingår i Biophysical Journal, s. 592A-592A, 2018.
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Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
Ingår i PLOS ONE, 2018.
DOI för Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI Ladda ner fulltext (pdf) av Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
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The Structural Basis for Initiation Factor 2 Activation during Translation Initiation
Ingår i Biophysical Journal, s. 593A-593A, 2018.
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tRNA tracking for direct measurements of protein synthesis kinetics in live cells
Ingår i Nature Chemical Biology, s. 618-626, 2018.
DOI för tRNA tracking for direct measurements of protein synthesis kinetics in live cells
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Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase
Ingår i Nucleic Acids Research, s. 11582-11593, 2017.
DOI för Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase Ladda ner fulltext (pdf) av Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase