Publications
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Antibiotic perseverance increases the risk of resistance development
Part of Proceedings of the National Academy of Sciences of the United States of America, 2023.
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Can molecular dynamics be used to simulate biomolecular recognition?
Part of Journal of Chemical Physics, 2023.
DOI for Can molecular dynamics be used to simulate biomolecular recognition?
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Real-time single-molecule 3D tracking in E. coli based on cross-entropy minimization
Part of Nature Communications, 2023.
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Rapid antibiotic susceptibility testing and species identification for mixed samples
Part of Nature Communications, 2022.
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Spatiotemporal kinetics of the SRP pathway in live E. coil cells
Part of Proceedings of the National Academy of Sciences of the United States of America, 2022.
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Spatiotemporally controlled generation of NTPs for single-molecule studies
Part of Nature Chemical Biology, p. 1144-+, 2022.
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A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation
Part of Molecular Cell, p. 1766-1780.e10, 2021.
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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
Part of Molecular Cell, p. 767-783.e11, 2021.
DOI for Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD Download full text (pdf) of Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
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Direct measurements of erythromycin’s effect on protein synthesis kinetics in living bacterial cells
Part of Journal of Molecular Biology, 2021.
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Imaging-based screens of pool-synthesized cell libraries
Part of Nature Methods, p. 358-365, 2021.
DOI for Imaging-based screens of pool-synthesized cell libraries
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More Than Just Letters and Chemistry: Genomics Goes Mechanics
Part of TIBS -Trends in Biochemical Sciences. Regular ed., p. 431-432, 2021.
DOI for More Than Just Letters and Chemistry: Genomics Goes Mechanics
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Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis
Part of EMBO Reports, 2021.
DOI for Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis Download full text (pdf) of Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis
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Real-time measurements of aminoglycoside effects on protein synthesis in live cells
Part of Proceedings of the National Academy of Sciences of the United States of America, 2021.
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Reconstructing the Evolutionary History of a Highly Conserved Operon Cluster in Gammaproteobacteria and Bacilli
Part of Genome Biology and Evolution, 2021.
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The highly dynamic nature of bacterial heteroresistance impairs its clinical detection
Part of Communications Biology, 2021.
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Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch
Part of Cell reports, 2020.
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Ornithine capture by a translating ribosome controls bacterial polyamine synthesis
Part of Nature Microbiology, p. 554-561, 2020.
DOI for Ornithine capture by a translating ribosome controls bacterial polyamine synthesis
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Rationally designed Spot 42 RNAs with an inhibition/toxicity profile advantageous for engineering E. coli
Part of ENGINEERING REPORTS, 2020.
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Recent advances in single-molecule fluorescence microscopy render structural biology dynamic
Part of Current opinion in structural biology, p. 61-68, 2020.
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RHS-elements function as type II toxin-antitoxin modules that regulate intra-macrophage replication of Salmonella Typhimurium
Part of PLOS Genetics, 2020.
DOI for RHS-elements function as type II toxin-antitoxin modules that regulate intra-macrophage replication of Salmonella Typhimurium Download full text (pdf) of RHS-elements function as type II toxin-antitoxin modules that regulate intra-macrophage replication of Salmonella Typhimurium
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Time-resolved imaging-based CRISPRi screening
Part of Nature Methods, p. 86-92, 2020.
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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling
Part of Nature Communications, 2019.
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Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase
Part of Chemical Science, p. 9699-9707, 2019.
DOI for Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase Download full text (pdf) of Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase
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Rotational and Translational Diffusion of Proteins as a Function of Concentration
Part of ACS Omega, p. 20654-20664, 2019.
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Single-Molecule Tracking Approaches to Protein Synthesis Kinetics in Living Cells
Part of Biochemistry, p. 7-14, 2019.
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Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition
Part of Nature Communications, 2019.
DOI for Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition Download full text (pdf) of Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition
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The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element
Part of Proceedings of the National Academy of Sciences of the United States of America, p. 15901-15906, 2019.
DOI for The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element Download full text (pdf) of The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element
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Tracking of single tRNAs for translation kinetics measurements in chloramphenicol treated bacteria
Part of Methods, p. 23-30, 2019.
DOI for Tracking of single tRNAs for translation kinetics measurements in chloramphenicol treated bacteria Download full text (pdf) of Tracking of single tRNAs for translation kinetics measurements in chloramphenicol treated bacteria
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Transcription and translation contribute to gene locus relocation to the nucleoid periphery in E. coli
Part of Nature Communications, 2019.
DOI for Transcription and translation contribute to gene locus relocation to the nucleoid periphery in E. coli Download full text (pdf) of Transcription and translation contribute to gene locus relocation to the nucleoid periphery in E. coli
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An early peak in ion channel research
Part of Nature Physics, p. 105-105, 2018.
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Biosynthesis of Translation Inhibitor Klebsazolicin Proceeds through Heterocyclization and N-Terminal Amidine Formation Catalyzed by a Single YcaO Enzyme
Part of Journal of the American Chemical Society, p. 5625-5633, 2018.
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Computing Curvature Sensitivity of Biomolecules in Membranes by Simulated Buckling
Part of Journal of Chemical Theory and Computation, p. 1643-1655, 2018.
DOI for Computing Curvature Sensitivity of Biomolecules in Membranes by Simulated Buckling
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Engineering a palette of eukaryotic chromoproteins for bacterial synthetic biology
Part of Journal of Biological Engineering, 2018.
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KN Direct phenotypic antimicrobial susceptibility testing under 30 minutes: Dynamics of single cell response revealed in automated microscopy with microfluidics
Part of Journal of Veterinary Pharmacology and Therapeutics, p. 17-17, 2018.
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New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites
Part of Chemical Science, p. 6233-6239, 2018.
DOI for New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites Download full text (pdf) of New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites
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Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
Part of PLOS ONE, 2018.
DOI for Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI Download full text (pdf) of Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
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Systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria
Part of Proceedings of the National Academy of Sciences of the United States of America, p. E4796-E4805, 2018.
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tRNA tracking for direct measurements of protein synthesis kinetics in live cells
Part of Nature Chemical Biology, p. 618-626, 2018.
DOI for tRNA tracking for direct measurements of protein synthesis kinetics in live cells
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Variational Algorithms for Analyzing Noisy Multistate Diffusion Trajectories
Part of Biophysical Journal, p. 276-282, 2018.
DOI for Variational Algorithms for Analyzing Noisy Multistate Diffusion Trajectories
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Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging
Part of Proceedings of the National Academy of Sciences of the United States of America, p. 9170-9175, 2017.
DOI for Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging
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Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously
Part of The FASEB Journal, p. 1204-1214, 2017.
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How Will Kinetics and Thermodynamics Inform Our Future Efforts to Understand and Build Biological Systems?
Part of CELL SYSTEMS, p. 144-146, 2017.
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In situ genotyping of a pooled strain library after characterizing complex phenotypes
Part of Molecular Systems Biology, 2017.
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Kinetics of dCas9 Target Search in Escherichia Coli
Part of Biophysical Journal, p. 314A-314A, 2017.
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Kinetics of dCas9 target search in Escherichia coli
Part of Science, p. 1420-1423, 2017.
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Measuring the Orientation of Single Proteins Interacting with DNA using Fluorescence Polarization Microscopy
Part of Biophysical Journal, p. 169A-169A, 2017.
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Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1
Part of Molecular Cell, p. 847-859.e7, 2017.
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Real- Time Single Protein Tracking with Polarization Readout using a Confocal Microscope
Part of Biophysical Journal, p. 295A-295A, 2017.
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Variation in Mutational Robustness between Different Proteins and the Predictability of Fitness Effects
Part of Molecular biology and evolution, p. 408-418, 2017.
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Curvature Sensing by a Viral Scission Protein
Part of Biochemistry, p. 3493-3496, 2016.
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Hypothesis: Homologous Recombination Depends on Parallel Search
Part of CELL SYSTEMS, p. 325-327, 2016.
DOI for Hypothesis: Homologous Recombination Depends on Parallel Search
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In Vivo Measurements of Protein Synthesis Kinetics using Single-Molecule Tracking of E.Coli tRNAS
Part of Biophysical Journal, p. 351A-351A, 2016.
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Quantification of transcription factor-DNA binding affinity in a living cell
Part of Nucleic Acids Research, p. 3045-3058, 2016.
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Simulated single molecule microscopy with SMeagol
Part of Bioinformatics, p. 2394-2395, 2016.
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The helical structure of DNA facilitates binding
Part of Journal of Physics A, 2016.