Synthetic biology, protein synthesis and drug discovery
SynBio is a creative new field defined as the complex engineering of replicating systems. It encompasses next-generation technology for bioengineering and fresh approaches to global challenges such as drug discovery and biofuels.
Our current projects include:
- Improving ribosomal incorporation of unnatural amino acids for investigating translation mechanism and for applications such as directed evolution of peptidomimetic drugs.
- Development of chromoproteins as reporters and for biosensor diagnostics.
- Understanding and improving transcription termination.
- Improving vaccines via synthetic biology.
Determining functions of ribosomal RNA modifications towards synthesis of the ribosome and self-replication.