The goal of our research is to improve the atomic level understanding of receptor-ligand interactions using computational models. Using physics-based methods such as molecular dynamics simulations and molecular docking, we focus on how small molecules interact with proteins and thereby modulate their function. Many of our research projects involve G protein-coupled receptors (GPCRs). This large family of membrane proteins plays essential roles in human physiology and contains numerous important drug targets. Visit our external homepage to read more about our research.
We are part of the Dept. of Cell and Molecular Biology and the Science for Life Laboratory (SciLifeLab) at Uppsala university. Our research is mainly funded by grants from SciLifeLab, the Swedish and European research councils.