Publikationer
-
Cerebrospinal fluid cytokines after autologous haematopoietic stem cell transplantation and intrathecal rituximab treatment for multiple sclerosis
Ingår i Brain Communications, 2023.
DOI för Cerebrospinal fluid cytokines after autologous haematopoietic stem cell transplantation and intrathecal rituximab treatment for multiple sclerosis Ladda ner fulltext (pdf) av Cerebrospinal fluid cytokines after autologous haematopoietic stem cell transplantation and intrathecal rituximab treatment for multiple sclerosis
-
N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents: design, synthesis, in vitro evaluation, and in silico studies
Ingår i RSC Advances, s. 399-420, 2023.
DOI för N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents: design, synthesis, in vitro evaluation, and in silico studies Ladda ner fulltext (pdf) av N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents: design, synthesis, in vitro evaluation, and in silico studies
-
A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models
Ingår i Journal for ImmunoTherapy of Cancer, 2022.
DOI för A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models Ladda ner fulltext (pdf) av A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models
-
Binding Networks Identify Targetable Protein Pockets for Mechanism-Based Drug Design
Ingår i International Journal of Molecular Sciences, 2022.
DOI för Binding Networks Identify Targetable Protein Pockets for Mechanism-Based Drug Design Ladda ner fulltext (pdf) av Binding Networks Identify Targetable Protein Pockets for Mechanism-Based Drug Design
-
Calculation of Heat Capacity Changes in Enzyme Catalysis and Ligand Binding
Ingår i Journal of Chemical Theory and Computation, s. 6345-6353, 2022.
DOI för Calculation of Heat Capacity Changes in Enzyme Catalysis and Ligand Binding Ladda ner fulltext (pdf) av Calculation of Heat Capacity Changes in Enzyme Catalysis and Ligand Binding
-
Cerebrospinal Fluid in Classical Trigeminal Neuralgia: An Exploratory Study on Candidate Biomarkers
Ingår i Biomedicines, 2022.
DOI för Cerebrospinal Fluid in Classical Trigeminal Neuralgia: An Exploratory Study on Candidate Biomarkers Ladda ner fulltext (pdf) av Cerebrospinal Fluid in Classical Trigeminal Neuralgia: An Exploratory Study on Candidate Biomarkers
-
Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C
Ingår i Molecular Oncology, s. 846-859, 2022.
DOI för Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C Ladda ner fulltext (pdf) av Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C
-
Effects of denosumab treatment on the expression of receptor activator of nuclear kappa-B ligand (RANKL) and TNF-receptor TNFRSF9 after total hip arthroplasty-results from a randomized placebo-controlled clinical trial.
Ingår i Osteoporosis International, s. 1-8, 2022.
DOI för Effects of denosumab treatment on the expression of receptor activator of nuclear kappa-B ligand (RANKL) and TNF-receptor TNFRSF9 after total hip arthroplasty-results from a randomized placebo-controlled clinical trial. Ladda ner fulltext (pdf) av Effects of denosumab treatment on the expression of receptor activator of nuclear kappa-B ligand (RANKL) and TNF-receptor TNFRSF9 after total hip arthroplasty-results from a randomized placebo-controlled clinical trial.
-
Exploring Non-orthosteric Interactions with a Series of Potent and Selective A(3) Antagonists
Ingår i ACS Medicinal Chemistry Letters, s. 243-249, 2022.
DOI för Exploring Non-orthosteric Interactions with a Series of Potent and Selective A(3) Antagonists Ladda ner fulltext (pdf) av Exploring Non-orthosteric Interactions with a Series of Potent and Selective A(3) Antagonists
-
Extracellular vesicles in heart failure: A study in patients with heart failure with preserved ejection fraction or heart failure with reduced ejection fraction characteristics undergoing elective coronary artery bypass grafting
Ingår i Frontiers in Cardiovascular Medicine, 2022.
DOI för Extracellular vesicles in heart failure: A study in patients with heart failure with preserved ejection fraction or heart failure with reduced ejection fraction characteristics undergoing elective coronary artery bypass grafting Ladda ner fulltext (pdf) av Extracellular vesicles in heart failure: A study in patients with heart failure with preserved ejection fraction or heart failure with reduced ejection fraction characteristics undergoing elective coronary artery bypass grafting
-
Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes
Ingår i Scientific Reports, 2022.
DOI för Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes Ladda ner fulltext (pdf) av Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes
-
GenErode: a bioinformatics pipeline to investigate genome erosion in endangered and extinct species
Ingår i BMC Bioinformatics, 2022.
DOI för GenErode: a bioinformatics pipeline to investigate genome erosion in endangered and extinct species Ladda ner fulltext (pdf) av GenErode: a bioinformatics pipeline to investigate genome erosion in endangered and extinct species
-
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction
Ingår i Journal of Medicinal Chemistry, s. 3473-3517, 2022.
DOI för Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction Ladda ner fulltext (pdf) av Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction
-
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A(1) Antagonists
Ingår i Journal of Medicinal Chemistry, s. 2091-2106, 2022.
DOI för Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A(1) Antagonists Ladda ner fulltext (pdf) av Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A(1) Antagonists
-
Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
Ingår i Cell Reports Medicine, 2022.
DOI för Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues Ladda ner fulltext (pdf) av Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
-
Re: Chen Dong, Sung-Lang Chen, and Wen-Wei Sung's Letter to the Editor re: Karin Welen, Ebba Rosendal, Magnus Gisslen, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285-93
Ingår i European Urology, s. E124-E125, 2022.
-
Reply to Carlos G. Wambier and Gerard J. Nau's Letter to the Editor re: Karin Welen, Ebba Rosendal, Magnus Gisslen, et al. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. Eur Urol. 2022;81:285-93. Positive Effects of Enzalutamide for Hospitalized COVID-19 Patients
Ingår i European Urology, s. E143-E144, 2022.
-
Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
Ingår i ACS Chemical Biology, s. 2744-2752, 2022.
DOI för Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5 Ladda ner fulltext (pdf) av Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
-
Synthesis of a Series of Novel 2-Amino-5-substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole Derivatives as Potential Anticancer, Antifungal and Antibacterial Agents
Ingår i Medicinal chemistry, s. 558-573, 2022.
-
The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease
Ingår i Molecular Neurobiology, s. 5955-5969, 2022.
DOI för The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease Ladda ner fulltext (pdf) av The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease
-
Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression
Ingår i Blood Advances SUPPLEMENTAL INFORMATION FOR: Transcriptomic analysis reveals pro-inflammatory signatures associated with acute myeloid leukemia progression SUPPLEMENTARY MATERIAL: Transcriptomic analysis reveals pro-inflammatory signatures associated with acute myeloid leukemia progression, s. 152-164, 2022.
DOI för Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression Ladda ner fulltext (pdf) av Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression
-
Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
Ingår i Journal of the American Chemical Society, s. 2905-2920, 2022.
DOI för Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses Ladda ner fulltext (pdf) av Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses
-
White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery
Ingår i Fluids and Barriers of the CNS, 2022.
DOI för White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery Ladda ner fulltext (pdf) av White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery
-
3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure–Activity Relationship Studies, and Enantiospecific Recognition
Ingår i Journal of Medicinal Chemistry, s. 458-480, 2021.
-
A Korteweg-DeVries type model for helical soliton solutions for quantum and continuum phenomena
Ingår i International Journal of Modern Physics C, 2021.
-
A practical guide to large-scale docking
Ingår i Nature Protocols, s. 4799-4832, 2021.
-
Accurate absolute free energies for ligand-protein binding based on non-equilibrium approaches
Ingår i Communications Chemistry, 2021.
DOI för Accurate absolute free energies for ligand-protein binding based on non-equilibrium approaches Ladda ner fulltext (pdf) av Accurate absolute free energies for ligand-protein binding based on non-equilibrium approaches
-
Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?
Ingår i PloS Computational Biology, 2021.
DOI för Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models? Ladda ner fulltext (pdf) av Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?
-
Classical molecular dynamics
Ingår i Journal of Chemical Physics, 2021.
-
Deciphering conformational selectivity in the A(2A) adenosine G protein-coupled receptor by free energy simulations
Ingår i PloS Computational Biology, 2021.
DOI för Deciphering conformational selectivity in the A(2A) adenosine G protein-coupled receptor by free energy simulations Ladda ner fulltext (pdf) av Deciphering conformational selectivity in the A(2A) adenosine G protein-coupled receptor by free energy simulations
-
Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines
Ingår i Journal of enzyme inhibition and medicinal chemistry (Print), s. 1553-1563, 2021.
DOI för Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines Ladda ner fulltext (pdf) av Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines
-
Fragment-based design of selective GPCR ligands guided by free energy simulations
Ingår i Chemical Communications, s. 12305-12308, 2021.
DOI för Fragment-based design of selective GPCR ligands guided by free energy simulations Ladda ner fulltext (pdf) av Fragment-based design of selective GPCR ligands guided by free energy simulations
-
Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets
Ingår i Blood Advances SUPPLEMENTAL INFORMATION FOR: Genomic characterization of adult and pediatric relapsed acute myeloid leukemia reveals novel therapeutic targets, s. 900-912, 2021.
-
Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines
Ingår i Journal of enzyme inhibition and medicinal chemistry (Print), s. 34-47, 2021.
DOI för Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines Ladda ner fulltext (pdf) av Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines
-
Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling
Ingår i eLIFE, 2021.
DOI för Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling Ladda ner fulltext (pdf) av Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling
-
Identification of V6.51L as a selectivity hotspot in stereoselective A(2B) adenosine receptor antagonist recognition
Ingår i Scientific Reports, 2021.
DOI för Identification of V6.51L as a selectivity hotspot in stereoselective A(2B) adenosine receptor antagonist recognition Ladda ner fulltext (pdf) av Identification of V6.51L as a selectivity hotspot in stereoselective A(2B) adenosine receptor antagonist recognition
-
Interpretable Machine Learning Reveals Dissimilarities Between Subtypes of Autism Spectrum Disorder
Ingår i Frontiers in Genetics, 2021.
DOI för Interpretable Machine Learning Reveals Dissimilarities Between Subtypes of Autism Spectrum Disorder Ladda ner fulltext (pdf) av Interpretable Machine Learning Reveals Dissimilarities Between Subtypes of Autism Spectrum Disorder
-
Ligand design by targeting a binding site water
Ingår i Chemical Science, s. 960-968, 2021.
-
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas
Ingår i Nature Communications, 2021.
DOI för Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas Ladda ner fulltext (pdf) av Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas
-
Microscopic origins of conductivity in molten salts unraveled by computer simulations
Ingår i Communications Chemistry, 2021.
DOI för Microscopic origins of conductivity in molten salts unraveled by computer simulations Ladda ner fulltext (pdf) av Microscopic origins of conductivity in molten salts unraveled by computer simulations