Department of Cell and Molecular Biology

Holmqvist Lab

Bacteria are constantly challenged by harsh conditions in their ever-changing natural environments. To survive and proliferate, bacterial cells cope with stressful conditions by rapidly re-wire gene expression. To this end, bacteria have acquired complex gene regulatory networks, which at the post-transcriptional level are dominated by RNA-binding proteins and regulatory small RNAs. We study molecular mechanisms and cellular functions of bacterial RNA-binding proteins and their RNA ligands to understand how these regulatory macromolecules contribute to bacterial growth and survival.

Read more in our popular science presentation or go directly to our ongoing research.