In my research group, we are interested in the mechanisms of RNA interference (RNAi) and cell-cell transport of RNA between cells in animals. In particular, we focus on the role of endolysosomes in these processes. We and others have previously shown that late endosomes and lysosomes affect RNAi and microRNA silencing efficiency as well as RNA transport, suggesting that these compartments are important for modulating the response to small RNAs. To be able to easily study these pathways in the context of a whole animal, we are using the nematode Caenorhabditis elegans. In addition to our main line of research, we strive to promote the use of C. elegans as a model organism in Uppsala and Sweden.