Department of Cell and Molecular Biology

Microbiology

Microbiology

The Microbiology program has over the years developed and conducted research that spans a wide range of projects in prokaryotic and eukaryotic microbiology. Topics are infection biology and protozoa, genomics and evolution of unicellular eukaryotes, antibiotic resistance and cost/benefit issues, RNA biology, bacterial and eukaryotic regulatory RNAs, the CRISPR-Cas adaptiveimmune system and its application, bacteriophages, toxin-antitoxin and contact-dependent growth inhibition systems, and more. Model organisms primarily but not exclusively used in these studies include Escherichia coli, Salmonella, Mycobacteria, Giardia lamblia, Caenorhabditis elegans, and Dictyostelium discoideum.
The Microbiology program is headed by Professor Staffan Svärd and consists at present of eleven research groups. For more information on research projects and personnel, see their respective web pages. The PI's/ group leaders and PhD students are strongly dedicated to, and involved in, teaching of various courses at all levels, and two of the Pi's have been appointed excellent teachers.
Members of the program are associated with SciLifeLab Uppsala, URRC (Uppsala RNA Research Center), and a NordForsk network on noncoding RNAs.

Research groups
  • Hellman Lab - Allergy/Vaccines
  • Hinas Lab - Membranes and vesicles in RNA interference and RNA transport
  • Holmqvist Lab - RNA-binding proteins
  • Kleinau Lab - Immunology and autoimmunity
  • Koskiniemi Lab - Growth inhibition in bacteria and the use of armed probiotics
  • Lundgren Lab - Biology and applications of the CRISPR-Cas immune system
  • Sellin Lab – The cell biology of gut bacterial infections
  • Svärd Lab - Parasitic protozoa-biology and disease mechanisms
  • Söderbom Lab - Small regulatory RNAs in social amoebae - functions during development and infection
  • Virtanen Lab - RNA biology in eukaryotes
  • Wagner Lab - Bacterial regulatory RNAs - biological functions and mechanisms of action